A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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Making use of single-molecule optical and AFM imaging and force-spectroscopy procedures, we request to unravel the mechanistic elements of the construction and dynamics of chromosomes. Our research pursuits incorporate:
It absolutely was only inside the nineteen nineties although, when nanotechnology experienced State-of-the-art to some amount in which one molecules might be manipulated, that the main experimental units commenced to appear.
Back in 1991, Sumio Iijima in the NEC Corporation had noted the synthesis of carbon nanotubes. Band construction calculations proposed that these nanotubes could exhibit metallic band conduction. This might be a big edge in excess of the conducting polymers we experienced explored, which have been, the truth is, disordered semiconductors presenting just variable-selection hopping conductivity.
Non-equilibrium folding of person DNA molecules recaptured as much as 1000 times inside a strong state nanopore
2010, formulated a completely new way (‘wedging transfer’) to manipulate nanostructures; initial report of DNA translocation by way of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into stable-state nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en achieved 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
He also discovered time to put in writing a number of textbooks, send Practically forty thousand tweets and guide a successful exploration group at Delft University of Technology. ‘It doesn’t come to feel like work’, he ceesdekker states. ‘I’m just terribly curious.’
‘You should not just think of the issues of tomorrow, but will also evaluate the questions of the working day after tomorrow’
Quite cool, but that wasn’t genuinely where by my interest lay. I wished to pioneer And that i had the feeling that was not doable, because the most appealing basic insights experienced now been uncovered. But my area experienced made numerous interesting new applications to measure personal molecules. I made a decision which i needed to apply this to biology, to look at it from a Bodily viewpoint.’
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
1999, initially measurement in the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for your new Luttinger description of interacting electrons in nanotubes
Developments in nanotechnology within the 1990s produced developing electronic gadgets from single molecules a chance. Cees Dekker recounts how his group designed a place-temperature transistor based upon one carbon nanotube.
2013, controlled shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations during the handedness of histone tetrasomes